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If a CNS lesion is present, the child will typically have a pubertal gonadotropin response to GnRH that is usually associated with idiopathic true precocious. .
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  • 5  Central precocious puberty occurs when the brain starts sending out signals for puberty to begin before the time when puberty would normally be expected.
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  • Key features of premature adrenarche.
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    Mar 1, 2016 · In girls, puberty typically begins with breast development between ages 8 and 13 and ends with menarche, or the first period.

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  • When passed from parent to child, the condition is known as familial central precocious puberty.
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    Thorough history and physical examination are critical.